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Serving Scientists Since 1994

USP 6 Rotating Cylinder Without Extension for Transdermal Testing

Part Number Pack Size Price Qty
APPSIX-01 Each

USP 6 rotating cylinder without extension for transdermal testing. Compatible with Distek, Hanson Research and Varian (VanKel)


OEM Part# 12-1360, 3200-0142

Apparatus

This QLA USP 6 rotating cylinder and extension for transdermal testing is compatible with all brands of dissolution bath and conforms exactly to the USP specification.

Transdermal or patch testing is carried out using USP method 5 (paddle over disc) or USP method 6 (the rotating cylinder).

 

Method

The rotating cylinder is very similar to USP method 1 (the rotating basket). With USP method 6 however, the basket assembly is replaced by a solid stainless steel cylinder.

The cylinder consists of two parts that fit together: the main shaft/cylinder assembly plus an extension. The extension is used when the transdermal patch requires a larger area.

Unlike dissolution testing, transdermal testing is carried out at 32°C to reflect the lower temperature of the skin. Other variables such as the height setting and sampling requirements are the same as dissolution testing.