USP5 Transdermal Patch Holder, 35mm, 40 Mesh

USP5 Transdermal Patch Holder 40 Mesh

Transdermal Patch Holder with 35mm (1.38") opening and 40 Mesh screen.

Use in Paddle Over Disk Applications

Method

Transdermal or patch testing is carried out using USP method 5 (paddle over disc) or USP method 6, the rotating cylinder.

With paddle over disc, the transdermal patch is placed between a glass disc and an inert PTFE mesh. This is placed at the bottom of the vessel, with the mesh facing upwards, under a rotating paddle.

Unlike dissolution testing, transdermal testing is carried out at 32°C to reflect the lower temperature of the skin. Other variables such as the height setting and sampling requirements are the same as dissolution testing. APPFIVE-V35 has an outer diameter of 41.2mm and meets the diagram in the USP.